The Role Of Moringa Leaf Extract (Moringa Oleifera) On Interleukin-10 Levels In Chronic Inflammation Of The Dermis Of White Wistar Rats (Rattus Norvegicus)

Traumatic injury can cause chronic inflammation that lasts several months to years. Interleukin-10 plays an important role in the repair of tissue fibrosis and accelerates wound healing. The active compounds secondary metabolites Moringa leaves include flavonoids, saponins, alkaloids, tannins accelerate closure act as anti-inflammatory effect help vasoconstriction blood vessels so minimize signs inflammation. aim this study was analyze leaf extract on levels dermis This used a true experimental research with post-test only control group design. procedure using 20 male Wistar rats, aging 2-3 months, weighing 150-200 grams divided into four groups, negative experiment treatment at concentration 5%, 10% 15%. administered for 3 days after creation dermis. Blood serum were taken administration extract. Analysis Kruskal Wallis 5% error rate. results showed p=0.040 (p<0.005), which means interleukin-10 significantly increased. oleifera had increasing white rats (Rattus norvegicus) best